| 7:30 am - 8:00 am |
Continental Breakfast |
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Foyer, 3rd floor Ocean Tower |
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| 8:00 am - 9:30 am |
Session V |
Pathogenesis of neurotropic viruses |
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Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower |
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Session Chairs |
Don Gilden and Monique Lafon |
| 8:00 am - 8:25 am |
Velpandi Ayyavoo
(Plenary Address) |
Insights into the role of HIV-1 Vpr in neuropathogenesis |
| 8:30 am - 8:55 am |
Howard Lipton
(Plenary Address) |
The role of apoptosis in Theiler’s virus persistence in mice |
| 9:00 am - 9:30 am |
Alan Jackson |
Rabies virus infection of dorsal root ganglia in experimental rabies and in cultured adult mouse dorsal root ganglia neurons: Selective vulnerability and evidence of oxidative stress |
| 9:30 am - 10:00 am |
Coffee Break |
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Foyer, 3rd floor Ocean Tower |
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| 10:00 am - 11:30 am |
Session VI |
Innate and adaptive immunity |
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Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower |
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Session Chairs |
Carol Shoshkes Reiss and Kenneth Williams |
| 10:00 am - 10:25 am |
Glen Barber
(Plenary Address) |
Restricting oncolytic vesicular stomatitis virus neurovirulence using miRNA strategy |
| 10:30 am - 10:55 am |
Bonnie Blomberg |
Molecular mechanisms for decreased antibody response in aged humans |
| 11:00 am - 11:25 am |
Tracy Fischer-Smith |
Modulation of HIV-1 replication, monocyte/macrophage phenotype, and cytokine gene expression, by tyrosine kinase inhibitors: A novel approach for pharmacotherapeutic intervention in HIV infection and NeuroAIDS |
| 11:30 am - 12:00 pm |
Special Lecture 8 |
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Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower |
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James Sejvar |
Neurological Infections Lectureship |
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Introduction |
Avindra Nath |
| 12:00 pm - 12:30 pm |
Investigators-in-Training Session III |
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Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower |
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Session Chairs |
Antonina Dolei and Valeria Pietropaolo |
| 12:00 pm - 12:10 pm |
Ilker Sariyer |
The cellular splicing factor, SF2/ASF, is a negative regulator of JC virus transcription and replication in glial cells |
| 12:15 pm - 12:25 pm |
David Boltz |
Spread of H5N1 influenza viruses in rat cortical neuron culture is effected by surface glycoproteins |
| 12:30 pm - 1:30 pm |
Lunch Break (on your own) |
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| 2:00 pm - 3:50 pm |
Workshop |
Molecular therapeutics & drug delivery |
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Salon 1A, 1st floor Ocean Tower |
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Workshop Chair |
Harris Gelbard |
| 2:00 pm - 2:25 pm |
Harris Gelbard |
Why is mixed lineage kinase activity so important to drug development for NeuroAIDS? |
| 2:25 pm - 2:40 pm |
Joseph Steiner |
New therapeutics development for HANDWhy is mixed lineage kinase activity so important to drug development for NeuroAIDS? |
| 2:40 pm - 2:55 pm |
Madhavan Nair |
Magnetic nanocarrier drug delivery system for targeting AZTTP and CTOP to brain |
| 2:55 pm - 3:10 pm |
Elias Argyris |
Novel proteoglycan-related molecular targets in HIV-1 infection of primary human macrophages: Implications for neuropathogenesis |
| 3:10 pm - 3:25 pm |
Ravi Mahalingam |
Latent simian varicella virus reactivates in monkeys treated with tacrolimus with or without exposure to irradiation |
| 3:25 pm - 3:50 pm |
Open Discussion |
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| 1:30 pm - 3:50 pm |
Workshop |
Demyelinating diseases and virus reactivation in disease modifying therapies |
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Salon 1B, 1st floor Ocean Tower |
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Workshop Chairs |
Steven Jacobson, Micheline McCarthy, and Antonina Dolei |
| 1:30 pm - 1:45 pm |
Henry McFarland |
Pathogenesis of Multiple Sclerosis |
| 1:45 pm - 1:55 pm |
Olaf Stuve |
Iatrogenic breakdown of CNS immunesurveillance as a potential contributing factor to opportunistic infections |
| 1:55 pm - 2:05 pm |
Antonina Dolei |
Regulation of MSRV (Multiple Sclerosis-associated retrovirus) and Syncytin-1 by viruses and cytokines |
| 2:05 pm - 2:15 pm |
Emilie Jaquiery* |
Increased EBV reactivation in the cerebrospinal fluid of patients with early Multiple Sclerosis |
| 2:15 pm - 2:25 pm |
S. Anna Sargsyan |
Epstein-Barr virus is not present in Multiple Sclerosis brain |
| 2:25 pm - 2:35 pm |
Jussi Virtanen |
Human herpesvirus 6 antibodies in Multiple Sclerosis |
| 2:35 pm - 2:40 pm |
Steven Jacobson |
Reactivation of human herpesvirus after natalizumab treatment in patients with Multiple Sclerosis |
| 2:40 pm - 2:48 pm |
Pasquale Ferrante |
Study of human polyomaviruses reactivation in Multiple Sclerosis patients during natalizumab therapy |
| 2:48 pm - 2:56 pm |
Igor Koralnik |
Subclinical reactivation of JC virus in blood and urine of Multiple Sclerosis patients treated with natalizumab |
| 2:56 pm - 3:04pm |
Cillian De Gascun |
Reactivation of latent viral infections in patients receiving natalizumab for the treatment of Multiple Sclerosis |
| 3:04 pm - 3:12 pm |
Emanuela Branchetti* |
Treatment of PBMC with the immunosuppressive drug Rituximab reactivates JC virus gene expression and replication in glial cells |
| 3:12 pm - 3:50 pm |
Open Discussion |
|
| 4:00 pm - 5:00 pm |
Investigators-in-Training Session IV |
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Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower |
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Session Chairs |
Walter Royal III and Adarsh Kumar |
| 4:00 pm - 4:10 pm |
Jieliang Li |
Interferon lambda inhibits herpes simplex virus type 1 replication in human neuronal cells |
| 4:15 pm - 4:25 pm |
Damien Chopy |
Role of LGP2, a cytoplasmic RIG-I-like helicase, on neuronal innate immune gene expression during rabies virus infection |
| 4:30 pm - 4:40 pm |
Laura B. Jaeger |
Migration of JC virus across the human blood-brain barrier occurs via clathrin-mediated endocytosis |
| 4:45 pm - 4:55 pm |
Saifur Rahman |
Modeling HTLV-1 infection and cellular immune response in HLA-A*0201 transgenic mice |
| 5:00 pm - 5:30 pm |
Special Lecture 9 |
Bill Narayan Lectureship |
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Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower |
|
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Janice Clements |
Unraveling the pathogenesis of HIV in the brain: Examining the SIV model during acute infection |
| |
Introduction |
Shilpa Buch |
| 6:30 pm – 7:30 pm |
Pioneer Reception |
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Ocean Tower Ballroom I, Salon C, 1st floor Ocean Tower |
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| 7:30 pm – 10:30 pm |
Pioneer Banquet |
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Ocean Tower Ballroom I, Salons A and B, 1st floor Ocean Tower |
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*Investigator-in-Training Awardee
