12:30 pm – 1:40 pm

Overview

12:30 pm

Dianne Rausch
Jeymohan Joseph

Division of AIDS Research, NIMH, NIH

Welcoming Remarks and Meeting Goals

12:40 pm

Steve Deeks

University of California,
San Francisco

HIV Cure and CNS

1:00 pm

David Margolis

University of North Carolina, Chapel Hill, NC

Translational Challenges in Targeting Latent HIV Infection

1:20 pm

Avindra Nath

Section of Infections of the Nervous System, NINDS, NIH

Challenges in the Eradication of HIV from the Brain

1:40 pm – 3:00 pm

In Vitro Models

1:40 pm

Ronald Swanstrom

University of North Carolina, Chapel Hill, NC

HIV Persistence in CNS and Myeloid Cells

2:00 pm

Mario Stevenson

University of Miami,
Miami, FL

In Vitro Model Systems to Study HIV Persistence in Macrophages

2:20 pm

Jonathan Karn

Case Western Reserve University, Cleveland, OH

Microglial Model Systems for Assessment of HIV-1 Latency

2:40 pm

Ruth Brack-Werner

German Research Center for Environmental Health, Munich, Germany

A novel model for proviral HIV-1 latency in neural cells reveals similarities between HIV-1 latency in the brain and in the immune system

3:00 pm – 3:20 pm

Break

3:20 pm – 4:00 pm

In Vivo Models

3:20 pm

Janice Clements

Johns Hopkins University, Baltimore, MD

An SIV Model to Identify and Eradicate Latent Viral Reservoirs in both T cells and Macrophages

3:40 pm

Victor Garcia-Martinez

University of North Carolina, Chapel Hill, NC

Mouse Model Systems to Study HIV Latency in the Myeloid Compartment

4:00 pm – 4:20 pm

Novel Technologies for HIV-CNS Eradication

4:00 pm

Kamel Khalili

Temple University, Philadelphia, PA

RNA Assisted Gene Surgery for Removal of Integrated HIV DNA from the Host Genome in the Brain

4:20 pm – 5:00 pm

Discussion

Co-Chairs:

Mario Stevenson
Avindra Nath

The Future Research Needs and Priorities for HIV CNS Eradication Research