Detailed Agenda - 9th International Symposium on Neurovirology

Friday, June 5th

7:30 am - 8:00 am Continental Breakfast  
  Foyer, 3rd floor Ocean Tower  
8:00 am - 9:30 am Session V Pathogenesis of neurotropic viruses
  Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower  
  Session Chairs Don Gilden and Monique Lafon
8:00 am - 8:25 am Velpandi Ayyavoo
(Plenary Address)
Insights into the role of HIV-1 Vpr in neuropathogenesis
8:30 am - 8:55 am Howard Lipton
(Plenary Address)
The role of apoptosis in Theiler’s virus persistence in mice
9:00 am - 9:30 am Alan Jackson Rabies virus infection of dorsal root ganglia in experimental rabies and in cultured adult mouse dorsal root ganglia neurons: Selective vulnerability and evidence of oxidative stress
9:30 am - 10:00 am Coffee Break  
  Foyer, 3rd floor Ocean Tower  
10:00 am - 11:30 am Session VI Innate and adaptive immunity
  Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower  
  Session Chairs Carol Shoshkes Reiss and Kenneth Williams
10:00 am - 10:25 am Glen Barber
(Plenary Address)
Restricting oncolytic vesicular stomatitis virus neurovirulence using miRNA strategy
10:30 am - 10:55 am Bonnie Blomberg Molecular mechanisms for decreased antibody response in aged humans
11:00 am - 11:25 am Tracy Fischer-Smith Modulation of HIV-1 replication, monocyte/macrophage phenotype, and cytokine gene expression, by tyrosine kinase inhibitors: A novel approach for pharmacotherapeutic intervention in HIV infection and NeuroAIDS
11:30 am - 12:00 pm Special Lecture 8  
  Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower  
  James Sejvar Neurological Infections Lectureship
  Introduction Avindra Nath
12:00 pm - 12:30 pm Investigators-in-Training Session III  
  Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower  
  Session Chairs Antonina Dolei and Valeria Pietropaolo
12:00 pm - 12:10 pm Ilker Sariyer The cellular splicing factor, SF2/ASF, is a negative regulator of JC virus transcription and replication in glial cells
12:15 pm - 12:25 pm David Boltz Spread of H5N1 influenza viruses in rat cortical neuron culture is effected by surface glycoproteins
12:30 pm - 1:30 pm Lunch Break (on your own)  
2:00 pm - 3:50 pm Workshop Molecular therapeutics & drug delivery
  Salon 1A, 1st floor Ocean Tower  
  Workshop Chair Harris Gelbard
2:00 pm - 2:25 pm Harris Gelbard Why is mixed lineage kinase activity so important to drug development for NeuroAIDS?
2:25 pm - 2:40 pm Joseph Steiner New therapeutics development for HANDWhy is mixed lineage kinase activity so important to drug development for NeuroAIDS?
2:40 pm - 2:55 pm Madhavan Nair Magnetic nanocarrier drug delivery system for targeting AZTTP and CTOP to brain
2:55 pm - 3:10 pm Elias Argyris Novel proteoglycan-related molecular targets in HIV-1 infection of primary human macrophages: Implications for neuropathogenesis
3:10 pm - 3:25 pm Ravi Mahalingam Latent simian varicella virus reactivates in monkeys treated with tacrolimus with or without exposure to irradiation
3:25 pm - 3:50 pm Open Discussion  
1:30 pm - 3:50 pm Workshop Demyelinating diseases and virus reactivation in disease modifying therapies
  Salon 1B, 1st floor Ocean Tower  
  Workshop Chairs Steven Jacobson, Micheline McCarthy, and Antonina Dolei
1:30 pm - 1:45 pm Henry McFarland Pathogenesis of Multiple Sclerosis
1:45 pm - 1:55 pm Olaf Stuve Iatrogenic breakdown of CNS immunesurveillance as a potential contributing factor to opportunistic infections
1:55 pm - 2:05 pm Antonina Dolei Regulation of MSRV (Multiple Sclerosis-associated retrovirus) and Syncytin-1 by viruses and cytokines
2:05 pm - 2:15 pm Emilie Jaquiery* Increased EBV reactivation in the cerebrospinal fluid of patients with early Multiple Sclerosis
2:15 pm - 2:25 pm S. Anna Sargsyan Epstein-Barr virus is not present in Multiple Sclerosis brain
2:25 pm - 2:35 pm Jussi Virtanen Human herpesvirus 6 antibodies in Multiple Sclerosis
2:35 pm - 2:40 pm Steven Jacobson Reactivation of human herpesvirus after natalizumab treatment in patients with Multiple Sclerosis
2:40 pm - 2:48 pm Pasquale Ferrante Study of human polyomaviruses reactivation in Multiple Sclerosis patients during natalizumab therapy
2:48 pm - 2:56 pm Igor Koralnik Subclinical reactivation of JC virus in blood and urine of Multiple Sclerosis patients treated with natalizumab
2:56 pm - 3:04pm Cillian De Gascun Reactivation of latent viral infections in patients receiving natalizumab for the treatment of Multiple Sclerosis
3:04 pm - 3:12 pm Emanuela Branchetti* Treatment of PBMC with the immunosuppressive drug Rituximab reactivates JC virus gene expression and replication in glial cells
3:12 pm - 3:50 pm Open Discussion  
4:00 pm - 5:00 pm Investigators-in-Training Session IV  
  Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower  
  Session Chairs Walter Royal III and Adarsh Kumar
4:00 pm - 4:10 pm Jieliang Li Interferon lambda inhibits herpes simplex virus type 1 replication in human neuronal cells
4:15 pm - 4:25 pm Damien Chopy Role of LGP2, a cytoplasmic RIG-I-like helicase, on neuronal innate immune gene expression during rabies virus infection
4:30 pm - 4:40 pm Laura B. Jaeger Migration of JC virus across the human blood-brain barrier occurs via clathrin-mediated endocytosis
4:45 pm - 4:55 pm Saifur Rahman Modeling HTLV-1 infection and cellular immune response in HLA-A*0201 transgenic mice
5:00 pm - 5:30 pm Special Lecture 9 Bill Narayan Lectureship
  Ocean Tower Ballroom II, Salons B and C, 3rd floor Ocean Tower  
  Janice Clements Unraveling the pathogenesis of HIV in the brain: Examining the SIV model during acute infection
  Introduction Shilpa Buch
6:30 pm – 7:30 pm Pioneer Reception  
  Ocean Tower Ballroom I, Salon C, 1st floor Ocean Tower  
7:30 pm – 10:30 pm Pioneer Banquet  
  Ocean Tower Ballroom I, Salons A and B, 1st floor Ocean Tower  

*Investigator-in-Training Awardee